Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Cov Khoom Ua Si hauv Kiwano Txiv Hmab Txiv Ntoo: Cov txiaj ntsig kev noj qab haus huv thiab kev nce qib tshiab hauv kev tsim dej haus
Nyob rau hauv lub neej niaj hnub no sai sai -paced niaj hnub txoj kev ua neej, ntau thiab ntau tus neeg tau txais kev pab nrhiav kev daws teeb meem los daws kev ntxhov siab thiab txhawb zog.Txiv hmab txiv ntoo(Acanthopanax senticosus txiv hmab txiv ntoo, tseem hu ua Eleuthero) tau dhau los ua cov khoom lag luam nrov hauv kev noj qab haus huv raws li nws tau lees paub los ntawm Tuam Tshoj National Health Commission raws li cov khoom tsim nyog siv rau hauv cov zaub mov noj qab haus huv. A 2021 tshuaj xyuas los ntawm Zhu Dan et al. systematically summarized nws lub ntsiab active cov khoom xyaw, kev noj qab haus huv functions, thiab haus dej haus kev loj hlob, muab ib tug ruaj khov scientific foundation rau functional dej haus innovation. Tsab ntawv xov xwm no muab cov kev tshawb fawb tshiab tshaj plaws los muab kev txhais lus dav dav ntawm kev noj qab haus huv ntawm kiwano txiv hmab txiv ntoo thiab tshawb nrhiav cov tswv yim siv ntawmkiwano ntshiab txiv hmab txiv ntoo hmoovthiabextract hmoovhauv cov khoom lag luam.
1. Cov khoom xyaw tseem ceeb ntawm Kiwano Txiv Hmab Txiv Ntoo: Lub Tsev Khoom Noj Khoom Haus
Kiwano txiv hmab txiv ntoo yog nplua nuj nyob rau hauv ntau yam bioactive tebchaw, uas tsim cov khoom hauv paus rau nws cov txiaj ntsig kev noj qab haus huv. Cov thawj qeb muaj xws li:
1.1 Glycosides
Glycosides yog cov khoom nquag tshaj plaws hauv kiwano txiv hmab txiv ntoo, suav nrog qab zib glycosides, saponins, thiab lignans. Ntawm lawv,Eleutheroside B thiab Emuaj cov ntsiab lus siab tshaj plaws, suav txog kwv yees li 80% ntawm tag nrho glycosides. Cov kev tshawb fawb qhia tau hais tias cov glycosides tuaj yeem muaj lawv cov piam thaj moieties tshem tawm tom qab nkag mus rau hauv lub cev, hloov mus rau hauv cov aglycones nquag uas ua rau cov teebmeem tseem ceeb. High- ntsuas ceev-tam sim no chromatography tau ntse cais siab -purity anthocyanins, nrog rau tag nrho cov ntsiab lus mus txog 1.2135 mg / g.
1.2 Flavonoids Cov
Flavonoids yog lwm qhov tseem ceeb ntawm kiwano txiv hmab txiv ntoo, feem ntau faib rau hauv cov txiv hmab txiv ntoo, nplooj, thiab cov hauv paus hniav. Siv cov surfactant-ultrasound extraction method, cov txheej txheem zoo ua tiav tag nrho cov flavonoid extraction tus nqi txog li 8.72%. Cov tshuaj txo cov tebchaw no muaj zog antioxidant muaj peev xwm.
1.3 Polysaccharides Cov
Polysaccharides hauv kiwano txiv hmab txiv ntoo yog feem ntau muaj fructose, qabzib, thiab arabinose. Dej-soluble thiab alkali-soluble polysaccharides account rau 2.3%–5.7% thiab 2%–6%, feem. Tom qab cov txheej txheem optimization, tus nqi rho tawm polysaccharide nce mus txog 10.88%. Ultrafiltration sib cais yields plaub molecular hnyav feem, nrog rau 50-10 u feem ntau yog 42.9%.
1.4 Minerals thiab Amino Acids
Kiwano txiv hmab txiv ntoo muaj 14 minerals xws li Fe, Zn, Sr, Mn, thiab Na, thiab muaj ib tug crude protein cov ntsiab lus ntawm 11.4% ntawm qhuav qhov hnyav. Qhov kev faib ua feem ntawm cov amino acids tseem ceeb ua tau raws li FAO / WHO cov qauv, ua rau nws yog cov nroj tsuag zoo heev -raws li cov protein.
1.5 Lwm yam Cheebtsam
Tsis tas li ntawd, nws muaj cov roj tsis hloov pauv, cov organic acids, tshiab acanthopanax phenols, pectin, thiab lwm yam khoom uas ua rau nws cov tsw thiab ua tau zoo.
Cov khoom xyaw nquag koom ua ke tsim lub hauv paus kev noj qab haus huv ntawm kiwano txiv hmab txiv ntoo.Kiwano ntshiab txiv hmab txiv ntoo hmoovthiabextract hmoovyog cov ntaub ntawv niaj hnub, yooj yim uas khaws cov khoom no kom yooj yim siv.
2. Tsib Cov txiaj ntsig kev noj qab haus huv ntawm Kiwano Txiv Hmab Txiv Ntoo (Tshwj xeeb los ntawm Cov Ntawv Pov Thawj Tshawb Fawb)
Ntau qhov kev sim tsiaj thiab cov xovtooj ntawm tes tau qhia txog cov txiaj ntsig kev noj qab haus huv hauv qab no ntawm kiwano txiv hmab txiv ntoo, ua rau nws tshwj xeeb tshaj yog haum rau kev noj qab haus huv niaj hnub los ntawm cov neeg nyob hauv nroog niaj hnub:
2.1 Los tiv thaiv-Cov teebmeem inflammatory
Kiwano dej extract tau txo qis xylene-induced pob ntseg o thiab qe dawb-induced paw o hauv nas. Fermented kiwano extract inhibits NO, iNOS, COX-2, thiab pro-inflammatory factor (IL-}6, TNF- ) hauv RAW264.7 macrophages, ua ib qho tseem ceeb ntawm cov tshuaj tiv thaiv kab mob.
2.2 Cov teebmeem Antioxidant
Eleutherosides thiab antioxidant enzymes tshem tawm cov dawb radicals thiab txhim kho lub cev muaj peev xwm antioxidant. Eleutheroside B txo cov ntshav lactate dehydrogenase thiab urea nitrogen hauv cov nas qaug zog thaum ua rau txoj hauv kev Nrf2 / HO-1. Syringin thiab Eleutheroside E kuj tiv thaiv daim siab thiab txo qis kev ua haujlwm transaminase.
2.3 Los tiv thaiv-Txoj kev qaug zog
Flavonoids thiab saponins ua rau kom cov leeg glycogen thiab siab glycogen qib, txhim kho LDH thiab SOD kev ua haujlwm, thiab txo cov ntshav lactic acid thiab urea nitrogen. Tsiaj thwmsim qhia tau hais tias kiwano extract prolongs tag nrho lub sij hawm ua luam dej nyob rau hauv nas, ua rau nws yog ib qho kev xaiv zoo tagnrho rau cov neeg nyiam noj qab haus huv thiab cov neeg ua haujlwm hauv chaw ua haujlwm.
2.4 Cov teebmeem Neuroprotective
Kiwano extract tiv thaiv neurons los ntawm inhibiting oxidative puas thiab o. Cov kev sim tshuaj ntsuam xyuas qhia tias kiwano txhaj tshuaj, thaum siv los ua ib qho ntxiv hauv kev kho neurasthenia, ua kom zoo dua qub thiab pab txhim kho kev pw tsaug zog zoo.
2.5 Kev tiv thaiv kev tiv thaiv kab mob
Kiwano polysaccharides qhib NF-κB txoj hauv kev thiab txhawb kev tsim cov IL-1 , IL-6, IL-10, thiab TNF- . Cov dej decoction ua kom cov ntshav hemolysin nce qib thiab spleen cell proliferation nyob rau hauv nas, pab txhawb ob qho tib si lom zem thiab cellular tiv thaiv.
Kiwano ntshiab txiv hmab txiv ntoo hmoovthiabextract hmoovmloog zoo rau cov khoom xyaw saum toj no, ua rau lawv nyiam cov ntaub ntawv ntxiv rau txhua hnub thiab txhim kho cov khoom lag luam -tshwj xeeb tshaj yog tsim nyog rau kev kho dua tshiab lossis ntxiv rau cov dej haus ua haujlwm.
3. Kev Tshawb Fawb Kev Txhim Kho hauv Kiwano Kev Tsim Kho Dej Haus: Los ntawm Raw Khoom mus rau cov khoom tiav
Nrog kev xav tau ntawm cov neeg siv khoom loj zuj zus rau "tshuaj kho mob-cov khoom noj homology" dej haus, kev vam meej tau ua tiav hauv kiwano dej haus kev txhim kho.Kiwano ntshiab txiv hmab txiv ntoo hmoovthiabextract hmoovtau dav siv los ua cov ntaub ntawv tseem ceeb hauv ntau yam khoom, khaws cia cov txiv hmab txiv ntoo cov ntsiab lus tseem ceeb thaum txhawb kev tsim khoom thiab kev hloov pauv.
3.1 Kiwano Txiv Hmab Txiv Ntoo Dej Haus
Txhawm rau hais txog qhov iab me ntsis ntawm kiwano, kev sim orthogonal tau txiav txim siab cov qauv zoo: 6% kua txiv, 7.5% sucrose, thiab 0.08% citric acid. Sivextract hmoovlos yog ntshiab txiv hmab txiv ntoo hmoov raws li concentrated raw khoom, ob homogenization (25 MPa, 60 degree) ua raws li los ntawm sterilization ntawm 100℃rau 10 feeb yields ib tug refreshing haus nrog ib chav tsev - kub txee lub neej ntawm 3 lub hlis.
3.2 Kiwano Tshuaj yej Haus
Kiwano tshuaj yej muaj cov teebmeem xws li tonifying Qi, ntxiv dag zog rau tus po thiab ob lub raum, thiab calming lub siab. Kev sim tsiaj tau lees paub tias nws nce SOD thiab GSH-Px kev ua haujlwm thaum txo MDA cov ntsiab lus, xa cov tshuaj tiv thaiv antioxidant thiab tiv thaiv- cov txiaj ntsig qaug zog.Kiwano ntshiab txiv hmab txiv ntoo hmoovfeem ntau yog siv rau kev npaj yooj yim ntawm tshuaj yej haus.
3.3 Fermented Kiwano Haus
Fermentation ho txhim kho tsw thiab ua tau zoo. Qhov zoo tshaj plaws muaj xws li cov kab mob acetic acid fermentation los yog Bifidobacterium fermentation.Cov extractmarkedly txhim kho fermentation efficiency. Tom qab optimizing compound stabilizers, cov dej haus ua kom muaj kev sib npaug qab zib - qaub saj. Cov kab mob lactic acid fermented mis nyuj haus kuj tau ua tiav kev lag luam.
3.4 Composite Functional Kiwano Haus
Kev sib xyaw nrog lwm cov tshuaj-cov khoom xyaw homology xws li Astragalus, jujube, longan, shiitake nceb, thiab goji berry ua tau zoo dua. Piv txwv suav nrog kiwano-longan composite dej haus thiab shiitake-kiwano cov dej haus kis las, ob qho tib si uas qhia tau zoo heev los tiv thaiv- kev qaug zog.Kiwano ntshiab txiv hmab txiv ntoo hmoovthiab extract tso cai rau kev tswj hwm ntawm tag nrho cov saponins thiab tag nrho cov flavonoids, txhim kho cov qhab nia thiab kev ua haujlwm ruaj khov.
Cov dej haus no tsis tsuas yog khaws cov khoom xyaw tseem ceeb ntawm kiwano tab sis kuj txhim khu kev ruaj ntseg thiab saj los ntawm kev ua niaj hnub.Pure txiv hmab txiv ntoo hmoovyog qhov zoo tagnrho rau kev tsim kho tsev, thaumrho tawmyog qhov zoo dua rau qhov loj -tej dej haus ntau lawm.
4. Kev xaus thiab yav tom ntej Outlook
Nrog nws cov khoom xyaw nplua nuj thiab ntau- cov txiaj ntsig kev noj qab haus huv, kiwano txiv hmab txiv ntoo tau dhau los ua cov khoom lag luam zoo rau kev tsim dej haus. Qhov tshwm sim ntawmkiwano ntshiab txiv hmab txiv ntoo hmoovthiabextract hmoovtau txuas ntxiv txo qhov kev txwv tsis pub siv, tso cai rau cov neeg siv khoom yooj yim kom yooj yim txaus siab rau nws cov txiaj ntsig kev noj qab haus huv. Nyob rau hauv lub neej yav tom ntej, ntsuab ua thev naus laus zis thiab ntau cov qauv sib xyaw yuav qhib qhov kev lag luam ntau dua.
Koj puas xav tau cov lus qhia ntxiv txog kiwano ntshiab txiv hmab txiv ntoo hmoov lossis extract, cov lus pom zoo tsim khoom, lossis hloov tshiab ntawm kev tshawb fawb tshiab? Xav tias dawb los tawm lus los yog tiv tauj peb rau kev sab laj kev tshaj lij. Pib koj txoj kev noj qab haus huv kiwano thiab txaus siab rau qhov tseem ceeb txhua hnub!
Cov ntaub ntawv: Kab lus no yog ua raws li Zhu Dan et al., "Kev Tshawb Fawb Txog Kev Tshawb Fawb Txog Cov Khoom Siv Ua Haujlwm, Kev Noj Qab Haus Huv Kev Noj Qab Haus Huv thiab Kev Loj Hlob ntawm Acanthopanax senticosus" (2021) thiab lwm yam kev tshawb fawb muaj cai. Cov zaub mov noj qab haus huv yuav tsum tau siv raws li cov lus qhia kho mob; Cov teebmeem yuav txawv ntawm tus kheej.
